I've been having the exact same issue, and interestingly also on an Optiplex 7050.
I solved it, though - in my case, it was light-locker. This seems to get installed by default with most desktops like xfce, but it has hidden settings to lock sessions on power down events and the like which don't appear in the XFCE or Gnome settings panels (and I assume not in KDE either)
From what I could work out, not having a battery in the 7050 caused some sort of confusion between it and upower, and so when the optiplex woke up light-locker has a lot of timers go off for events and it flooded so many screen damage events ("session Locked! No it's not. Session locked! No it's not......") that Chrome, most times, just crashed.
Setting light-locker's settings to 0 might have worked, but seriously this is not easy to do!
So, Chrome is badly written (which we know) but light-locker is not particularly useful on the optiplex setup, so easiest fix - just remove the light-locker package and reboot. Haven't had the issue since, and upower alone handles my screen blanking and sleep just fine, and you can always install xscreensaver if you want that sort of thing.